Reproductive Technologies and the Risk of Birth Defects — NEJM: Although the large majority of births resulting from assisted conception were free of birth defects, treatment with assisted reproductive technology was associated with an increased risk of birth defects, including cerebral palsy, as compared with spontaneous conception. In the case of ICSI, but not IVF, the increased risk of birth defects persisted after adjustment for maternal age and several other risk factors. Although we cannot rule out the possibility that other patient factors contribute to or explain the observed associations, our findings can help provide guidance in counseling patients who are considering treatment for infertility.
Translation please! Here are a couple articles that put the above in plain English:
Risk of major birth defects in fertility babies almost double, research finds
In vitro fertilization off the hook for causing birth defects
Related:
Fertility treatment only partly responsible for increase in birth defects
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