British Bioethics Council Gives OK to Three-Parent Embryo | LifeNews.com: There are two different ways to approach the making of a embryo with 3 genetic parents. In the first method, called pronuclear transfer, doctors would take the nucleus out of an embryo that had a mutation in his or her mtDNA and put it into an embryo whose mtDNA was normal, after removing the nucleus of that embryo of course. (For an illustration of this method click here.) The alternative method, called maternal spindle transfer, would be to remove the nucleus of an egg from a woman with mitochondrial disease, place it into a donor egg with normal mtDNA (after the nucleus of that egg was removed) and then fertilize the engineered egg with sperm. In either technique, the result is an embryo with the nuclear DNA from its mother and father and the mtDNA from another woman.
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